LONG MU QING XIN MIXTURE IMPROVES BEHAVIORAL PERFORMANCE IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR/NCRL) BY UPREGULATING CATECHOLAMINE NEUROTRANSMITTERS IN PREFRONTAL CORTEX AND STRIATUM VIA DRD1/CAMP/PKA-CREB SIGNALING PATHWAY

Long Mu Qing Xin mixture improves behavioral performance in spontaneously hypertensive rats (SHR/NCrl) by upregulating catecholamine neurotransmitters in prefrontal cortex and striatum via DRD1/cAMP/PKA-CREB signaling pathway

BackgroundAttention deficit hyperactivity disorder (ADHD), a prevalent neurodevelopmental disorder in children, can be effectively alleviated by the herbal preparation Long Mu Qing Xin Mixture (LMQXM), but its mechanism has not been fully elucidated.ObjectiveTo scrutinize the potential pharmacological mechanisms by which LMQXM improves behavior in

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Transcriptional Profiling of CD8+ CMV-Specific T Cell Functional Subsets Obtained Using a Modified Method for Isolating High-Quality RNA From Fixed and Permeabilized Cells

Previous studies suggest that the presence of antigen-specific polyfunctional T cells is correlated with improved pathogen clearance, disease control, and clinical outcomes; however, the molecular mechanisms responsible for the generation, function, and survival of polyfunctional T cells remain unknown.The study of polyfunctional T cells has been,

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Socio-economic and political responses to regional polarisation and socio-spatial peripheralisation in Central and Eastern Europe: a research agenda

In the past years, new patterns of regional disparities between metropolised core regions and the remaining parts of Central and Eastern European countries (CEE) have emerged.Such spatial disparities have lately fuelled concerns about further Measurement regional polarisation and the peripheralisation of non-metropolitan regions in particular.This

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